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Pertussis (Whooping Cough)

by 댕그리쌤 2024. 11. 19.
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Pertussis (Whooping Cough)

Causes

Pertussis is caused by the bacterium Bordetella pertussis. It is highly contagious and spreads through respiratory droplets from coughing or sneezing.


Symptoms

Pertussis has three stages:

  1. Catarrhal Stage (1-2 weeks)
    • Symptoms resemble a common cold:
      • Runny nose
      • Mild fever
      • Mild cough
    • This stage is the most contagious.
  2. Paroxysmal Stage (1-6 weeks)
    • Characterized by severe coughing fits followed by a "whooping" sound during inhalation.
    • Other symptoms:
      • Vomiting after coughing
      • Exhaustion after coughing spells
      • Difficulty breathing in severe cases
  3. Convalescent Stage (2-3 weeks or longer)
    • Gradual recovery with a decrease in coughing episodes, although they can persist for weeks.

Treatment

  1. Antibiotics
    • Macrolides such as azithromycin, erythromycin, or clarithromycin are commonly used.
    • Early treatment can help reduce symptoms and transmission but may have limited effect once severe symptoms develop.
  2. Supportive Care
    • Hydration is essential.
    • In severe cases, hospitalization may be required, especially for infants, to manage complications like apnea or pneumonia.
  3. Preventive Measures for Close Contacts
    • Antibiotics may be given to family members or others in close contact with the infected individual to prevent further spread.

Prognosis (Outlook)

  • Infants: High risk of severe complications such as pneumonia, seizures, and encephalopathy.
  • Children and Adults: Typically recover well, although persistent cough may last weeks to months.
  • With timely medical intervention, the prognosis is generally favorable, especially for older children and adults.

Prevention of Pertussis (Whooping Cough)

Preventing pertussis is crucial, especially for protecting infants and vulnerable populations. Here are detailed measures:


1. Vaccination

The most effective way to prevent pertussis is through immunization.

  • DTaP Vaccine (Diphtheria, Tetanus, and Pertussis):
    • Recommended for children in a series of five doses at 2, 4, 6, 15-18 months, and 4-6 years.
    • Provides immunity during early childhood.
  • Tdap Booster (Tetanus, Diphtheria, and Pertussis):
    • For adolescents (11-12 years) and adults who missed previous boosters.
    • Pregnant women should receive a Tdap vaccine during each pregnancy, preferably between 27-36 weeks gestation, to pass immunity to the newborn.
  • Cocooning Strategy:
    • Vaccinate close family members, caregivers, and anyone in contact with infants to create a protective "cocoon" around the baby.

2. Isolation and Hygiene

  • Limit Contact with Infected Individuals:
    • Avoid close contact with people showing symptoms of pertussis.
    • Keep infected individuals home from school, daycare, or work until they've completed at least five days of antibiotic treatment.
  • Hand Hygiene:
    • Wash hands frequently with soap and water for at least 20 seconds.
    • Use alcohol-based hand sanitizers when soap isn’t available.
  • Cough Etiquette:
    • Cover mouth and nose with a tissue or elbow when coughing or sneezing.
    • Dispose of tissues immediately and wash hands afterward.

3. Antibiotic Prophylaxis

  • For close contacts of infected individuals, antibiotics may be prescribed to prevent the spread of pertussis, especially in high-risk groups like:
    • Infants under 12 months
    • Pregnant women in the third trimester
    • People with weakened immune systems

4. Public Health Measures

  • Awareness Campaigns: Educate the public on the importance of vaccinations and early symptom recognition.
  • School and Workplace Policies: Enforce rules to stay home when symptomatic to reduce outbreaks.

5. Avoid Exposure During Outbreaks

  • During community outbreaks, take extra precautions to avoid crowded places and maintain proper ventilation in indoor areas.

By combining vaccination, good hygiene practices, and public health strategies, the risk of pertussis can be significantly reduced. Vaccination remains the cornerstone of prevention, as it provides both personal protection and community-level immunity.

 
 

 

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